Dr. Ren Silva
Psychiatrist · Mood disorders

Making the science of mood disorders simple

Mood disorders are the only thing I work on, and bipolar disorder most of all. Every week I read the new research and write up the three findings that actually matter.

2016 On mood disorders since
900,000+ Followers across platforms
114 million Content views
Dr. Ren Silva, psychiatrist, seated at a table in a library.

Dr. Ren Silva, MD · Licensed in Brazil

ISBD (International Society for Bipolar Disorders) member since 2021

A decade dedicated to bipolar disorder

Writing, teaching, building technology and reading the literature. It’s four fronts and one mission: make life better for the people who live with the condition.

The books

Three books on mood disorders. One for the person who just got the diagnosis and for the family around them, and two for the clinicians who treat it. They don’t read the same way, and they aren’t meant to.

3Books published

See the books

Teaching the clinicians

This is the work that multiplies. Every class I finish carries the subject into practices I’ll never set foot in, and reaches patients I’ll never meet.

400+Physicians and psychologists trained

institutoith.com.br

The app and the AI platform

I founded and run Estabiliza, the tracking app that’s free for the person with the diagnosis, and the AI platform that supports the clinician. More than 15,000 people track their mood in it, and it holds over 70,000 check-ins.

80,000+App downloads

appestabiliza.com

The weekly letter

What’s New in Mood Disorders. A search runs against PubMed every morning, and once a week the three findings that survive go out in plain English. It’s short because the filter is strict.

TuesdaysA new letter every week

How it’s written

Three books, two audiences

One written for the person who’s just been diagnosed and for the family around them. Two written for the clinicians who treat it. The same mission, in two vocabularies.

Cover of the book Bipolar No Mysteries, from diagnosis to a better life, by Dr. Ren Silva.

4.9

rating on more than 400 reviews of the Portuguese original

Bipolar No Mysteries

I wrote it for two people at the same time: the one who just got the diagnosis, and the one who loves them and can’t tell whether what they’re watching is the condition or the person.

It moves from what bipolar disorder is, through the medications and what they’re doing inside the brain, into the rhythms that carry a stable year. No technical term gets past a paragraph without a plain sentence beside it, because a term you can’t picture is a term you won’t keep.

The English edition is its own book, written for an American reader rather than translated from the Portuguese one, and it isn’t out yet. What you can buy today is the Portuguese original, and that’s the edition the rating above belongs to.

02

Foundations of the Specialization in Mood Disorders

Technical volume for physicians and psychologists. Published in Portuguese.

2022

03

Understanding Bipolar Disorder

Editor in chief and scientific coordinator of a collective volume with more than 60 contributing authors, psychiatrists and psychologists. Published in Portuguese.

2026

Dr. Ren Silva reading in an armchair beside a lamp and a wall of books.
Every week

I read the journals so the letter can be short

A search runs against PubMed every morning for new work on bipolar and mood disorders. Reviews and opinion pieces don’t make it. Primary studies stay, ranked by journal, quartile and study design. About fourteen papers survive a week, and three of them make the letter. That’s the whole filter.

The letter also says why one study made it and another one didn’t, which is the part an aggregator can’t do for you. Technical terms get a plain sentence beside them, because “individual participant data meta-analysis” means nothing to anybody until somebody says out loud that they went back to the raw numbers instead of the summaries.

14Papers read a week
3Findings that make the letter

Six questions I keep coming back to

Every video, episode and chapter lands somewhere in this list. It hasn’t changed much in ten years, because the questions haven’t.

Bipolar or unipolar

Two depressions that look identical from the outside and pull treatment in opposite directions. It’s the fork with the highest cost of getting it wrong, and on average it isn’t reached for years.

Mania and hypomania

What the diagnosis actually rests on, and why hypomania slips past almost everybody. If a stretch of weeks didn’t feel like a problem, nobody thinks to report it.

Bipolar next to ADHD and borderline

Three conditions that share a symptom list and don’t share much else. Telling them apart is where medical training earns its keep, and it’s the question the internet answers worst.

Medication, and what it really does

What a mood stabilizer is doing in the brain, what it isn’t doing, and how to read the trade between a side effect you can feel today and a relapse you can’t see coming.

Sleep and biological rhythm

The part of treatment that isn’t a pill, and it’s rarely prescribed with any precision. Most stable years are won or lost here, weeks before anything shows up on a symptom scale.

Cognition and function

Concentration, memory and speed after the episode ends. It’s the strongest single predictor of how life actually goes, it doesn’t lift when the mood does, and almost nobody hears about it up front.

Where the science circulates every day

YouTube

@DrRenSilvaEnglish

Watch

Podcast

Bipolar No Mysteries, on Spotify

Listen

TikTok

@drrensilva

Follow

LinkedIn

The founder and platform side of the work

Connect

I met bipolar disorder as a son before I studied it as a doctor.

Dr. Ren Silva

My mother lives with the condition. For years we didn’t have a name for what was happening at home, and that’s the gap everything on this page keeps trying to close.

Black and white portrait of Dr. Ren Silva.

The training behind the work

I’m a psychiatrist, licensed in Brazil, and mood disorders are the only thing I work on. Not psychiatry broadly, not mental health broadly. One family of conditions, every day since 2016.

I graduated in medicine at the Federal University of Uberlândia and trained in psychiatry at the University of São Paulo’s teaching hospital in Ribeirão Preto. Everything I’ve built since sits on the same mission: the books, the training programs for clinicians, the app, the podcast and the channels. My work in the United States is educational, editorial and technological.

Academic exchange in medicine University of Siena, Italy · 2009
Doctor of Medicine Federal University of Uberlândia · 2011
Psychiatry residency Hospital das Clínicas, Ribeirão Preto, University of São Paulo · 2016
Clinical research in the mental health graduate program Ribeirão Preto Medical School, University of São Paulo · 2018
Member of the International Society for Bipolar Disorders ISBD, ID 36211 · since 2021

Start with this week’s letter

What’s New in Mood Disorders goes out every Tuesday morning. It’s three findings from the new research on bipolar disorder and depression, in plain English, written by the psychiatrist who reads the papers.

Get the weekly letter

Simplify to transform.